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Lewis and Clark Trail ~From Sea to Shining Sea ~ Suggested Itinerary
Departure City - Destination City Miles Field Notes
 Cincinnati, Ohio - Clarksville/Indiana, Louisville, Kentucky 101 miles You are here

The Ohio River Scenic Highway

Clarksville, Indiana/Louisville, Kentucky On October 14, 1803, Meriwether Lewis and William Clark met in Louisville, Kentucky, thus forming one of the most famous and successful partnerships in history.  On October 26, 1803, Lewis and Clark together with the nucleus of the Corps of Discovery, set off down the Ohio River on their westward journey, returning in November 1806.

Kentucky Derby Museum, Louisville, Kentucky: Located at Churchill Downs, the museum chronicles the history of this historic track and the Kentucky Derby, including information on Meriwether Lewis Clark, Jr., the grandson of William Clark, and the founder of both Churchill Downs and the Kentucky Derby.

704 Central Ave, Louisville, KY 40208-1212

Historic Locust Grove, Louisville, Kentucky: Locust Grove is a National Historic Landmark on 55 acres of the original 694 acre farm established by William and Lucy Clark Croghan in 1790.

561 Blankenbaker Ln, Louisville, KY 40207-1168

Filson Historical Society, Louisville, Kentucky: Holds a nationally significant Lewis and Clark collection. Items include six expedition date letters written by William Clark and one by Meriwether Lewis; letters, a diary, and documents related to the expedition; 1817 portrait of Clark; bighorn sheep collected during the journey. 

1310 S 3rd St, Louisville, KY 40208-2306

The Belvedere/Riverfront Plaza, Louisville, Kentucky:  Features the YORK Statue dedicated on October 14, 2003. 

Falls of the Ohio State Park and Interpretive Center, Clarksville, Indiana: A statue of Lewis and Clark was dedicated to the memory of Stephen E. Ambrose on October 26, 2003. 

201 W Riverside Dr, Clarksville, IN 47129-3148
Travel Notes: This a region rich in history and tradition. For centuries before the coming of the Europeans it was home to a succession of native cultures who established villages along the Ohio River and its tributaries. When French and English explorers began arriving during the 18th century, they encountered bands belonging to such tribes as the Shawnee, Miami, Potawatomi, and Wyandotte.

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